Synthesis of methyleneoxyamino derivatives of 1-butylthioheptane

Synthesis of 1-propylsulfanylhexane aminomethoxy derivatives

“…In extension of our studies in the field of nitrogencontaining alkylthioalkanes [9][10][11] we report here on the results of the synthesis and study of the properties of 1-propyl-sulfanylhexane aminomethoxy derivatives. To this end first we carried out a reaction of equimolar amounts of propanethiol (I) and 1-bromohexan-2-ol (II) in alkaline medium (40% water solution of NaOH) at 40-50°C for 3-4 h to obtain previously unknown sulfurcontaining secondary alcohol 1-propylsulfanylhexan-2-ol (III) in 67% yield (Scheme 1).…”

N,N,N′,N′-tetramethylmethanediamine, efficient reagent for thioles aminomethylation

“…Aminosulfi des were obtained in high yields and selectivity.Organic compounds containing nitrogen and sulfur are used as effi cient plant protecting substances[1-3], antioxidants, anticorrosion, antiscoring, and antiwear additives to fuels and lubricants [4][5][6][7][8][9][10].Up to now one of the most known methods for the synthesis of aminosulfi des remains the classic Mannich aminomethylation of thiols by secondary amines and aldehydes [11], but this procedure possesses certain limitations. For instance, the thiols aminomethylation using formaldehyde and dimethylamine occurs with relatively low yields [12] due to the application and dosing of the water solutions of the initial reagents.…”

“…Organic compounds containing nitrogen and sulfur are used as effi cient plant protecting substances[1-3], antioxidants, anticorrosion, antiscoring, and antiwear additives to fuels and lubricants [4][5][6][7][8][9][10].…”