Synthesis of intramolecular cross-coupling analogues of forskolin

Skeletal Transformations of Terpenoid Forskolin Employing an Oxidative Rearrangement Strategy

“…Previously, a series of forskolin analogues have been reported, − including the redox rearrangement products, acid-catalyzed rearrangement products, and base-catalyzed rearrangement products (Figure S12). , The base-catalyzed rearrangement product 3 bears a unique 6/7/5 tricyclic carbon skeleton, an oxygen bridging ring, making it an ideal precursor for next oxidative rearrangements (Scheme ).…”