Synthesis of (E)‐β‐Iodovinyl Sulfones via HI‐mediated Vicinal Iodosulfonylation of Alkynes with Sodium Sulfinates

Abstract

Hydroiodic acid‐mediated vicinal iodosulfonylation reaction of alkynes with sodium sulfinates is proposed for the synthesis of (E)‐β‐iodovinyl sulfones. The method is easy to operate, environmentally friendly, using inexpensive and easily available raw materials, and giving the target products with good regio‐ and stereoselectivity in satisfactory yields.