Synthesis of cis-Cu(gly)2·H2O, trans-Cu(gly)2, and cis-Ni(gly)2(H2O)2 and their Characterization Using Thermal and Spectroscopic Techniques—A Capstone Inorganic Laboratory

Cagle, Ethan C.; Stanford, Victoria L.; Nikles, Jacqueline A.; Gray, Gary M.

doi:10.1021/acs.jchemed.9b00631

Cited by 2 publications

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References 20 publications

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“…The use of capstone experiences, recommended in the Boyer Commission Report, benefits students by practicing an assortment of end-of-degree skills and knowledge in various contexts. In recent years, numerous reports of capstone experiences have been reported. − This version of such an experiment was recently implemented in a fourth-year advanced laboratory course in 2019 and Fall 2020. This experiment was developed, augmented, and enhanced in 2018 by undergraduate researchers.…”

Section: Introductionmentioning

confidence: 99%

Buchwald–Hartwig Amination, High-Throughput Experimentation, and Process Chemistry: An Introduction via Undergraduate Laboratory Experimentation

et al. 2021

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This three-part laboratory experiment investigates key aspects of the Buchwald−Hartwig amination cross-coupling reaction through guided-inquiry learning strategies. The first part of this experiment utilizes high-throughput experimentation techniques to reinforce, explore, and extend fundamental concepts that are represented in the classroom, including the use of air-free Schlenk techniques and heteronuclear NMR analysis. The second component challenges students to evaluate their results to design, set up, and perform a preparative-scale Buchwald−Hartwig amination. Finally, students purify and isolate their products using column chromatography allowing them to fully characterize their target molecules through a variety of analytical techniques. This experiment represents one of the final experiments performed in the fourth-year undergraduate chemistry curriculum and serves as a capstone learning experience for students.

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