2011
DOI: 10.1002/app.34273
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Synthesis of hyperbranched polycarbosilane modified with cyclodextrin derivatives and its application in coated capillary electrophoresis columns

Abstract: A series of hyperbranched polycarbosilanes were synthesized and coated on the inner surface of fused-silica capillaries by chemical bonding. The end groups of the hyperbranched polycarbosilanes were modified with b-cyclodextrin derivatives. The chiral isomers of ofloxacin and chlorpheniramine were separated by this new type of chiral capillary electrophoresis column and high-column efficiency was achieved. The results showed that ofloxacin was completely separated at pH 3.0; the separation resolution was 2.32,… Show more

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Cited by 11 publications
(10 citation statements)
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“…Covalent coating of fused‐silica capillaries with a hyperbranched polycarbosilane polymer functionalized with HP‐β‐CD as chiral selector represents an interesting strategy for the preparation of OT‐CEC columns . The capillary with immobilized HP‐β‐CD was tested for the enantioseparation of ofloxacine and chlorpheniramine and showed baseline and partial resolution, respectively, using 40 mM phosphate buffer, pH 3.0, as mobile phase.…”
Section: New Chiral Stationary Phases and Recent Applications Of Enanmentioning
confidence: 99%
“…Covalent coating of fused‐silica capillaries with a hyperbranched polycarbosilane polymer functionalized with HP‐β‐CD as chiral selector represents an interesting strategy for the preparation of OT‐CEC columns . The capillary with immobilized HP‐β‐CD was tested for the enantioseparation of ofloxacine and chlorpheniramine and showed baseline and partial resolution, respectively, using 40 mM phosphate buffer, pH 3.0, as mobile phase.…”
Section: New Chiral Stationary Phases and Recent Applications Of Enanmentioning
confidence: 99%
“…Various chemical reactions can be used to prepare SiC macromolecular precursors, and among them the hydrosilylation reaction is of great interest, leading to polymers with only Si, C and H elements in their structure. More particularly, dendritic and hyperbranched structures have attracted a lot of attention, but few studies were performed on the rheological behaviour of such macromolecular materials, especially during their synthesis by monitoring their complex transformation . Particularly, the ability to synthesize gel‐like polymers with controlled kinetics could be very useful for generating porous ceramics or aerogels …”
Section: Introductionmentioning
confidence: 99%
“…More specific optically active, photoresponsive, liquid crystalline, or polyhedral oligomeric silsesquioxane‐based hyperbranched polysiloxanes have also been prepared. Owing to the high degree of functionalization (leading to higher reactivity and higher molecular interactions) and the high flexibility of hyperbranched polysiloxanes, and as they keep a low viscosity and a good solubility, they have been proposed as highly reactive additives for resines, crosslinkers, macroinitiator for radical polymerization, supported catalysts, or stationary phase for capillary electrophoresis …”
Section: Introductionmentioning
confidence: 99%
“…Owing to the high degree of functionalization (leading to higher reactivity and higher molecular interactions) and the high flexibility of hyperbranched polysiloxanes, and as they keep a low viscosity and a good solubility, they have been proposed as highly reactive additives for resines, 33,39 crosslinkers, 41 macroinitiator for radical polymerization, 49 supported catalysts, 50 or stationary phase for capillary electrophoresis. 51 In our case, a one-pot strategy has been selected to prepare poly(siloxysilane)s in which the hyperbranched core is prepared by hydrosilylation of 1,7-octadiene (a bifunctional "B 2 " reagent) with the cyclic siloxane 2,4,6,8-tetramethylcyclotetrasiloxane (a tetrafunctional "A 4 " reagent). In this case, mixtures of, for example, A 3 B, A 2 B 2 , or AB 3 units are expected to be formed as intermediates during the reaction and are responsible for the branching.…”
mentioning
confidence: 99%