Abstract:Amines Q 0120 Synthesis of Hindered Tertiary Amines by a Mild Reductive Amination Procedure. -The operationally simple process involves the reductive amination of primary and secondary amines using the Hantzsch ester as the reductant. Ketones [cf. (VIIIa)] do not react thus allowing selective transformation of mixed substrates [cf. (VIIIb)]. -(MENCHE*, D.; BOEHM, S.; LI, J.; RUDOLPH, S.; ZANDER, W.; Tetrahedron Lett. 48 (2007) 3, 365-369; Med. Chem.,
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