Synthesis of Highly Fluorescent Gold Nanoparticles for Sensing Mercury(II)

Huang, Chih‐Ching; Yang, Zusing; Lee, Kun‐Hong; Chang, Huan‐Tsung

doi:10.1002/anie.200700803

Cited by 696 publications

(487 citation statements)

References 46 publications

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“…Another possibility is energy transfer from AgNC to the nearby Cu 2+ . Chang and co-workers synthesized carboxyl-capped AuNCs and showed fluorescence quenching induced by Pb 2+ , Hg 2+ or Cd 2+ [122]. In this case, quenching was likely related to AuNC aggregation since these metal ions could be chelated by the surface carboxyl ligands.…”

Section: Reactive Quenchersmentioning

confidence: 98%

DNA-stabilized, fluorescent, metal nanoclusters for biosensor development

Liu

2014

TrAC Trends in Analytical Chemistry

194

141

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In the past decade, fluorescent silver, gold and copper nanoclusters (Ag, Au and CuNCs) have emerged as a new class of signaling moiety for biosensor development. Compared to semiconductor quantum dots, metal NCs have less toxicity concerns and can be more easily conjugated to biopolymers. Due to their extremely small size, these NCs need a stabilizing ligand. Many polymers, proteins and nucleic acids have been reported to stabilize NCs. In particular, many DNA sequences produce highly fluorescence NCs. Coupling these DNA stabilizers with other sequences such as aptamers has generated a large number of biosensors. In this review, the synthesis of DNA and nucleotide-templated NCs is first summarized; their chemical interactions are also discussed. In the second part, the properties of NCs such as fluorescence quantum yield, emission wavelength and lifetime, structure and photostability are briefly reviewed. In the last part, various sensor design strategies using these NCs are categorized into the following four classes: 1) fluorescence de-quenching; 2) generation of templating DNA sequences to produce NCs; 3) change of nearby environment; and 4) reacting with heavy metal ions or other quenchers. Finally, the future trends in this field are discussed.

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Section: Reactive Quenchersmentioning

confidence: 98%

DNA-stabilized, fluorescent, metal nanoclusters for biosensor development

Liu

2014

TrAC Trends in Analytical Chemistry

194

141

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“…The interaction of Hg 2+ with the acid groups induced the aggregation of 11-MUA-Au NCs, resulting in the fluorescence quenching of 11-MUA-Au NCs. An LOD of 5.0 nM was obtained [94].…”

Section: Science China Materialsmentioning

confidence: 99%

Recent developments on nanomaterials-based optical sensors for Hg2+ detection

Duan

Zhan

2015

Sci. China Mater.

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Mercuric ion (Hg 2+ ), released from both natural and industrial sources, has severe adverse effects on human health and the environment even at very low concentrations. It is very important to develop a rapid and economical method for the detection of Hg 2+ with high sensitivity and selectivity. Nanomaterials with unique size and shape-dependent optical properties are attractive sensing materials. The application of nanomaterials to design optical sensors for Hg 2+ provides a powerful method for the trace detection of Hg 2+ in the environment, because these optical sensors are simple, rapidly responsive, cost-effective and highly sensitive. This review summarizes the recent advances on the development of optical assays for Hg 2+ in aqueous solution by using functionalized nanomaterials (including noble metal nanoparticles, fluorescent metal nanoclusters, semiconductor quantum dots and carbon nanodots). Detection strategies based on the Hg 2+ -induced changes in spectral absorbance, fluorescence intensity and surface-enhanced Raman scattering signals were described. And the design principles for each optical assay were presented. In addition, the future challenge and the prospect of the development of nanomaterial optical sensors for Hg 2+ detection were also discussed.

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“…, with limit of detection (LOD) 5 nM [6]. In the presence of Hg 2+ , photoluminescence quenching of 11-MUA-Au NDs occurs, due to the Au-Hg aurophilic interaction and aggragation of the Au NDs through the interaction of Hg 2+ ions with the carboxylate groups present on the surfaces of the 11-MUA-Au NDs.…”

Section: +mentioning

confidence: 99%

“…Au NDs can be prepared from etching of small Au nanoparticles (< 3 nm in diameter) by thiol compounds such as 11-mercaptoundecanoic acid (11-MUA) under alkaline conditions [6]. On the other hand, proteins such as bovine serum albumin (BSA), lysozyme, and horseradish peroxidase as a template and reducing agent are commonly used to prepare stable Au NCs [7].…”

mentioning

confidence: 99%

Photoluminescent Gold Nanomaterials as Sensitive Probes

Chang¹

2017

IJBSBE

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Synthesis of Highly Fluorescent Gold Nanoparticles for Sensing Mercury(II)

Cited by 696 publications

References 46 publications

DNA-stabilized, fluorescent, metal nanoclusters for biosensor development

DNA-stabilized, fluorescent, metal nanoclusters for biosensor development

Recent developments on nanomaterials-based optical sensors for Hg2+ detection

Photoluminescent Gold Nanomaterials as Sensitive Probes

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