Synthesis of (Hexaconazole-Zinc/Aluminum-Layered Double Hydroxide Nanocomposite) Fungicide Nanodelivery System for Controlling Ganoderma Disease in Oil Palm

Mustafa, Isshadiba Faikah; Hussein, Mohd Zobir; Saifullah, Bullo; Idris, Abu Seman; Hilmi, Nur Hailini Zainol; Fakurazi, Sharida

doi:10.1021/acs.jafc.7b04222

Cited by 23 publications

(35 citation statements)

References 18 publications

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“…The band at 1022 cm −1 was due to the phosphate group of TPP [38]. Moreover, a band at 3206 cm −1 corresponded to the OH group of hexaconazole [39]. Therefore, a band at 3218 cm −1 of the synthesized nanoparticles CHEN2.5, CHEN5, CHEN10, and CHEN20 was due to the combination of bands of hydrogen bonding of the chitosan–TPP and hexaconazole.…”

Section: Resultsmentioning

confidence: 99%

“…All the synthesized nanoparticles showed the chitosan–TPP characteristic bands with a slight shifting of the bands at 1653, 1549, 1059 cm −1 . Moreover, additional bands of hexaconazole can be seen for the synthesized nanoparticles at 1390, 890, 806, and 658 cm -1 which can be attributed to the C–N stretching, C=C bending, and C–Cl stretching, respectively [39], thus proving the encapsulation of hexaconazole into the chitosan matrix.…”

Section: Resultsmentioning

confidence: 99%

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Preparation of Chitosan–Hexaconazole Nanoparticles as Fungicide Nanodelivery System for Combating Ganoderma Disease in Oil Palm

et al. 2019

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Fungicide is used to control fungal disease by destroying and inhibiting the fungus or fungal spores that cause the disease. However, failure to deliver fungicide to the disease region leads to ineffectiveness in the disease control. Hence, in the present study, nanotechnology has enabled the fungicide active agents (hexaconazole) to be encapsulated into chitosan nanoparticles with the aim of developing a fungicide nanodelivery system that can transport them more effectively to the target cells (Ganoderma fungus). A pathogenic fungus, Ganoderma boninense (G. boninense), is destructive to oil palm whereby it can cause significant loss to oil palm plantations located in the Southeast Asian countries, especially Malaysia and Indonesia. In regard to this matter, a series of chitosan nanoparticles loaded with the fungicide, hexaconazole, was prepared using various concentrations of crosslinking agent sodium tripolyphosphate (TPP). The resulting particle size revealed that the increase of the TPP concentration produced smaller particles. In addition, the in vitro fungicide released at pH 5.5 demonstrated that the fungicide from the nanoparticles was released in a sustainable manner with a prolonged release time up to 86 h. On another note, the in vitro antifungal studies established that smaller particle size leads to lower half maximum effective concentration (EC50) value, which indicates higher antifungal activity against G. boninense.

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Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Preparation of Chitosan–Hexaconazole Nanoparticles as Fungicide Nanodelivery System for Combating Ganoderma Disease in Oil Palm

et al. 2019

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“…The consolidation of agronanochemicals in the production of crops is fundamentally founded on the control of some plant diseases. Like nanosensors, the investigation in this area has quite recently been initiated [ 104 ]. The appraisals of disease were assessed based on the antifungal activity of agronanofungicides on G. boninense fungus (in vitro).…”

Section: Prospectives Of Nanoformulations In Managing Plant Pathogenic Fungimentioning

confidence: 99%

“…Notwithstanding, not many investigations on the glasshouse or field assessment of utilizing agronanofungicides in controlling fungal diseases were carried out. A system of fungicide nanocarrier utilized by Mustafa et al was designed by entrapping the fungicide in aluminum/zinc-layered double hydroxide (Al-Zn-LDH) by means of the ion exchange technique [ 104 ]. The type of fungicides utilized are dazomet and hexaconazole, which were recently demonstrated to be powerful on the fungus G. boninense [ 105 ].…”

Section: Prospectives Of Nanoformulations In Managing Plant Pathogenic Fungimentioning

confidence: 99%

Trends in Nanotechnology and Its Potentialities to Control Plant Pathogenic Fungi: A Review

Kutawa

Ahmad

Ali

et al. 2021

Biology

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Approximately 15–18% of crops losses occur as a result of animal pests, while weeds and microbial diseases cause 34 and 16% losses, respectively. Fungal pathogens cause about 70–80% losses in yield. The present strategies for plant disease control depend transcendently on agrochemicals that cause negative effects on the environment and humans. Nanotechnology can help by reducing the negative impact of the fungicides, such as enhancing the solubility of low water-soluble fungicides, increasing the shelf-life, and reducing toxicity, in a sustainable and eco-friendly manner. Despite many advantages of the utilization of nanoparticles, very few nanoparticle-based products have so far been produced in commercial quantities for agricultural purposes. The shortage of commercial uses may be associated with many factors, for example, a lack of pest crop host systems usage and the insufficient number of field trials. In some areas, nanotechnology has been advanced, and the best way to be in touch with the advances in nanotechnology in agriculture is to understand the major aspect of the research and to address the scientific gaps in order to facilitate the development which can provide a rationale of different nanoproducts in commercial quantity. In this review, we, therefore, described the properties and synthesis of nanoparticles, their utilization for plant pathogenic fungal disease control (either in the form of (a) nanoparticles alone, that act as a protectant or (b) in the form of a nanocarrier for different fungicides), nano-formulations of agro-nanofungicides, Zataria multiflora, and ginger essential oils to control plant pathogenic fungi, as well as the biosafety and limitations of the nanoparticles applications.

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“…However, no work on the in vivo evaluation using agronanochemicals in the management of BSR disease has been reported. A fungicide nanodelivery system employed by Mustafa et al was made by intercalating fungicide in the zinc/aluminum layered-double hydroxide (Zn-Al-LDH) via the ion exchange method [142,143]. The fungicides used are hexaconazole and dazomet, which have been previously proven to be effective against G. boninense [39,144], and resulted in H-Zn-Al-LDH and D-Zn-Al-LDH, respectively.…”

Section: Agronanochemicals In Oil Palm Cultivationmentioning

confidence: 99%

An Overview of the Oil Palm Industry: Challenges and Some Emerging Opportunities for Nanotechnology Development

2020

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The increase in the world’s oil demand due to the rise of the global population urges more research into the production of sustainable vegetable oilseeds, among which palm oil is the most suitable candidate as it is the most efficient oilseed crop in the world. In an effort to drive the oil palm industry in the areas of food safety and security nanotechnology could offer a sustainable alternative. However, the utilization of nanotechnology in the oil palm industry is still limited. In this review, we aim to encourage the researchers to fully utilize nanotechnology as an alternative solution to tackle the challenges faced by the oil palm industry. Moreover, we also aim to highlight the opportunities for nanotechnology development in oil palm-based related research. The major points are as follows: (1) Nanosensing enables real-time monitoring of plantation status and crop progression, including soil, water and nutrient management, early pest/disease detection, and the spreading of pests/diseases. The use of nanosensing conveniently extends into advanced breeding topics, such as the development of disease-tolerant plants; (2) Nanotechnology could be the answer for the development of integrated management of pest and disease. Active agricultural ingredients can be entrapped or encapsulated into nanocarrier systems to improve their solubility, stability, enhance their efficient delivery to site-specific targets, with longer shelf life, and consequently improved efficacy; (3) Valuable nanomaterials can be isolated and generated from oil palm biomass waste. The utilization of oil palm biomass waste could overcome the issue of the massive production of waste in the oil palm industry and palm oil mills, where oil only accounts for 10% of the biomass, while 90% is comprised of the generated biowastes. (4) Palm oil can be utilized as a green alternative as a capping and stabilizing agent in the biosynthesis of metallic and non-metallic nanoparticles. In addition, nanoemulsion formulations using palm oil in drug delivery systems offer advantages such as low toxicity, enhance bioavailability and solubility of the drugs, apart from being inexpensive and environmentally friendly.

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Synthesis of (Hexaconazole-Zinc/Aluminum-Layered Double Hydroxide Nanocomposite) Fungicide Nanodelivery System for Controlling Ganoderma Disease in Oil Palm

Cited by 23 publications

References 18 publications

Preparation of Chitosan–Hexaconazole Nanoparticles as Fungicide Nanodelivery System for Combating Ganoderma Disease in Oil Palm

Preparation of Chitosan–Hexaconazole Nanoparticles as Fungicide Nanodelivery System for Combating Ganoderma Disease in Oil Palm

Trends in Nanotechnology and Its Potentialities to Control Plant Pathogenic Fungi: A Review

An Overview of the Oil Palm Industry: Challenges and Some Emerging Opportunities for Nanotechnology Development

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