Abstract:Azoles are prominent scaffolds in pharmaceutical arena. In fact, medicinal properties of azole and benzazole containing compounds include anticancer, antimicrobial, and antioxidant. Some of the drugs Inthomycin C, Oxaprozin, Tiazofurin, Dacarbazine, Tipifarnib, Albendazole, Febendazole, Omeprazole possess azole / benzazole moiety. Realizing the importance of azoles and benzazoles, it is planned to conjugate these two ligands as heteroaryl substituted urea derivatives and to study their antimicrobial activity. … Show more
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