Synthesis of halogenated benzimidazolyl-C-nucleosides and their activity against Leishmania major and Leishmania tropica

Abstract

Here we report the short synthesis of “reversed” halogenated C-nucleoside (benzimidazole) analogs. Initially, 1,2 ; 3,4 vicinal diols of D-galactose were acetylated with two different ketones, acetone and cyclohexanone, to...