Synthesis of fucosyllactose using α-L-fucosidases GH29 from infant gut microbial metagenome
Eva M. Moya-Gonzálvez,
Birgitte Zeuner,
Albert Th. Thorhallsson
et al.
Abstract:Fucosyl-oligosaccharides (FUS) provide many health benefits to breastfed infants, but they are almost completely absent from bovine milk, which is the basis of infant formula. Therefore, there is a growing interest in the development of enzymatic transfucosylation strategies for the production of FUS. In this work, the α-L-fucosidases Fuc2358 and Fuc5372, previously isolated from the intestinal bacterial metagenome of breastfed infants, were used to synthesize fucosyllactose (FL) by transfucosylation reactions… Show more
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