Synthesis of Fluoren‐9‐ones via Pd‐Catalyzed Annulation of 2‐Iodobiphenyls with Vinylene Carbonate
Wenguang Li,
Yongqi Yu,
Jie Yang
et al.
Abstract:A palladium‐catalyzed reaction for intermolecular selective C−H cyclocarbonylation of 2‐iodobiphenyls is described. Intriguingly, the vinylene carbonate acts as a carbon monoxide transfer agent to enable the annulation reaction. Moreover, as a versatile synthon, fluoren‐9‐one can be transformed into a variety of functionalized organic molecules, such as [1,1′‐biphenyl]‐2‐carboxylic acid, 1′H,3′H‐spiro[fluorene‐9,2′‐perimidine] and N‐tosylhydrazones.
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