“…41 It was shown that compounds 62 in reaction with isocyanides in different solvents formed a mixture of two isomeric heterocycles, namely, 2-substituted 5-amino [1,2,4] The structure of key compounds was proven by X-ray diffraction analysis. 41 An effective copper-catalyzed synthesis of N-substituted heterocycles using ligands for the formation of the C-N bond was discussed in the work of Subramanian and Kaliappan 42 (Scheme 38). It was shown, that 2-(1H-imidazol-1-yl)-aniline (112a), 2-(1H-benzimidazol-1-yl)aniline (112b), or 2-(1H-1,2,4-triazol-1-yl)aniline (112c) reacted with 2-bromopyridines 113 in DMF in the presence of copper(II) acetate, potassium phosphate, and ligands (phenanthroline monohydrate or tetrabutylammonium iodide) affording 9-phenyl-9H-imidazo[1,2-a]benzimidazole (114a), 5-phenyl-5H-benzimidazo[1,2-a]benzimidazole (114b), or 4-phenyl-4H- [1,2,4]triazolo[1,5-a]benzimidazole (114c), respectively.…”