Synthesis of ditertiary phenylenetetraacetylenic glycols of the piperidine series

Experimental and density functional theory studies of the novel piperidine-containing acetylene glycols

“…Thus, during the reaction in a medium without solvent, it becomes possible to examine the reaction products due to their purity and stability. 1 H NMR spectra were recorded on a Jeol JNM-ECA 400 NMR spectrometer (400 MHz) with HMDS as the internal standard. 13 C NMR spectra (100 MHz) were also recorded with this spectrometer.…”

“…A prospective solution to the hunger problem may be offered through compounds that have the ability to increase crop yield, for example by making crops more drought resistant. It is well known that the use of piperidine-containing diacetylene glycols may increase the growth of plants multifold [1][2][3][4][5]. In addition, plants which were processed by piperidine-containing diacetylene glycols prove to be more resistant to drought, temperature changes and diseases [1][2][3][4][5].…”

“…Piperidine-containing compounds have shown great promise as plant growth stimulators [1][2][3][4][5] ( Figure 1). Nowadays in the world one out of eight people does not get enough food.…”

“…Dimerization of acetylenic glycols is provided by oxidation in the presence of cuprous (I) chloride (Cu 2 Cl 2 ) and pyridine. 1,2,5 In the present work a new type of compounds with potentially similar positive effects on crop yield and drought resistance was synthesized and studied both experimentally and theoretically. Piperidine-based acetylene glycols were synthesized under the Favorskii reaction.…”

“…Piperidine-containing compounds have shown great promise as plant growth stimulators [1][2][3][4][5] (Fig 1).…”