Synthesis of Dialkyl Phosphoroselenocyanatidates and Their Rearrangement to Dialkyl Phosphoroiso-selenocyanatidates

Studies on the interaction of phosphine selenides and their structural analogues wth dihalogens and sulfuryl chloride

“…However the unstable 23 was prepared from O,O-dineopentyl-O-trimethylsilylselenophosphate. 12 Additional experiments involving ligand exchange at the phosphorus center and independent synthesis of these systems supported the phosphonium structure of the products obtained from the reaction of O,O,O-trialkylselenophosphates with dihalogens.…”

Selenium-Derivatized Oligonucleotides

“…Phosphane selenides, 1 phosphoroselenonoates, and isomeric phosphoroselenoloates, 2 phosphoroselenocyanidates, 3 and phosphoroisoselenocyanates 4 were considered as excellent model compounds for studies on the mechanisms of nucleophilic substitution at phosphorus atom, molecular rearrangements, chemical transformations, and structural assignments. Direct selenium-phosphorus bond expanded the array of P-chiral organophosphates making them excellent model compounds for stereochemical studies on nucleophilic and metal-ion assisted substitution at P-atom, as well as intermediates for stereocontrolled conversions to other important classes of compounds, e.g., dinucleoside methanephosphonates.…”