Synthesis of degradants and impurities of rabeprazole

Abstract

Rabeprazole is an antiulcer drug comes under the Pharmacological class (antisecretory compounds) which is Proton-pump inhibitor, and It's used for heartburn, acid reflux and GORD (gastro-oesophageal reflux disease). Rabeprazole is also used to prevent and treat stomach ulcers. We have observed some of the metabolite and impurities during the process of synthesis of Rabeprazole. The main aim of the present work is to synthesis and characterisation of impurities and metabolites.