Synthesis of cyclotriveratrylene dendrimers and their supramolecular complexes with fullerene C₆₀

Cyclotriveratrylene Dendrimers with a Fullerene C60 in the Dendritic Branches

“…The allyl ethers of 2 can then be cleaved back to phenols under mild condition, giving 3 in ca. 47 % [25].…”

“…Dendrimers with polyamidoamine (PAMAM), Polyarylethyl or polyethers groups have applications in drug delivery [20][21][22][23] and dendrimers with polyethers in their structure could be used as biodegradable dendrimers with the appropriate enzyme in the drug delivery systems [24]. Recently, we reported the synthesis of cyclotriveratriyene-dendrimers and their supramolecular complexes with the fullerene C 60 [25]. In the present work we report the synthesis of cyclotriveratrylene-dendrimers with three and six fullerenes in the dendritic branches.…”

“…Then, after most of the solvent was stripped off, water was added and the organic material was extracted with dichloromethane. This product was recrystallized from 100 ml of diethyl ether to yield 14 g (80 %) of a white powder [25].…”

“…The resulting purple solid was incubated at room temperature for 48 h. The reaction mixture was redissolved by addition of dichloromethane and the organic phase was thoroughly washed with water until neutral pH. The dichloromethane solution was partially dried over sodium sulphate and evaporated under vacuum, after which, ether was added, affording a crystalline residue, which was purified by digestion in 200 ml of ether overnight and finally isolated by suction filtration, to yield 0.22 g (37 %) of a white powder [25].…”

“…The organic filtrate was thoroughly washed with water, dried over sodium sulphate and concentrated to 5 ml. The desired triphenol, which was allowed to crystallize overnight, was finally collected by suction filtration, to yield 0.42 g (55 %) of white needles [25].…”