Synthesis of cyclodextrin-based polyrotaxanes and polycatenanes for supramolecular pharmaceutical sciences

Higashi, Taishi; Taharabaru, Toru; Motoyama, Keiichi

doi:10.1016/j.carbpol.2024.122143

Carbohydrate Polymers

2024

DOI: 10.1016/j.carbpol.2024.122143

|View full text |Cite

Synthesis of cyclodextrin-based polyrotaxanes and polycatenanes for supramolecular pharmaceutical sciences

Taishi Higashi,

Toru Taharabaru,

Keiichi Motoyama

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...

Citation Types

Supporting

Mentioning

Contrasting

Year Published

2024

Publication Types

Select...

Article1

Relationship

Self Cite0

Independent1

Authors

Journals

Cited by 1 publication

References 104 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

The Motility of β-Cyclodextrins Threaded on the Polyrotaxane Based Triblock Polymer and Its Influences on Mechanical Properties

Wang,

Niu,

Geng

et al. 2024

Materials

View full text Add to dashboard Cite

Polyrotaxane (PR) has garnered increasing attention due to its unique structure and exceptional performance. In this study, a polypseudorotaxane (PPR) initiator was prepared through the self-assembly of bromine-capped Pluronic F68 and β-cyclodextrins (β-CD) in water. Polyrotaxane-containing triblock copolymers (PR copolymers) were successfully synthesized by atom transfer radical polymerization (ATRP) of butyl methacrylate (BMA) using the PPR initiator in the presence of Cu(I)Br/PMDETA. The structure of the PR copolymers was thoroughly characterized using infrared spectroscopy (IR), proton nuclear magnetic resonance (1H NMR), and gel permeation chromatography (GPC). The mobility of β-CD in the PR copolymers was demonstrated through dielectric measurements. Mechanical tests, including tensile strength assessments, thermal mechanical analysis, and dynamic mechanical analysis, confirmed the excellent mechanical properties and good processability of the PR copolymer, attributed to the PBMA blocks. Furthermore, the mechanical properties were found to be modulated by the motility of the threaded β-CDs. Consequently, the superior mechanical properties and the high mobility of the threaded β-CDs suggest promising potential for the as-prepared PR polymer in various advanced applications.

show abstract

The Motility of β-Cyclodextrins Threaded on the Polyrotaxane Based Triblock Polymer and Its Influences on Mechanical Properties

Wang,

Niu,

Geng

et al. 2024

Materials

View full text Add to dashboard Cite

show abstract

scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.

Contact Info

hi@scite.ai

10624 S. Eastern Ave., Ste. A-614

Henderson, NV 89052, USA

Blog Terms and Conditions API Terms Privacy Policy Contact Cookie Preferences Do Not Sell or Share My Personal Information

Made with 💙 for researchers

Part of the Research Solutions Family.

Synthesis of cyclodextrin-based polyrotaxanes and polycatenanes for supramolecular pharmaceutical sciences

Cited by 1 publication

References 104 publications

The Motility of β-Cyclodextrins Threaded on the Polyrotaxane Based Triblock Polymer and Its Influences on Mechanical Properties

The Motility of β-Cyclodextrins Threaded on the Polyrotaxane Based Triblock Polymer and Its Influences on Mechanical Properties

Contact Info

Product

Resources

About