Synthesis of Coumarins with 3:4-Fused Ring Systems and their Physiological Activity

A facile and efficient synthesis of 2-amino-3-cyano-4H-chromenes and tetrahydrobenzo[b]pyrans using 2,2,2-trifluoroethanol as a metal-free and reusable medium

“…4H-Pyran can also serve as useful building blocks in the generation of a variety of natural products showing molluscicidal, antibacterial, anticancer, antitubercular, antimicrobial, anti-coagulant, antiallergic, antibiotic, hypolipidemic, and immunomodulating activities [13][14][15][16][17][18][19][20]. In addition, they can be used as cognitive enhancers, for the treatment of neurodegenerative disease, including Alzheimer's disease, amyotrophic lateral sclerosis, Huntington's disease, Parkinson's disease, AIDS associated dementia and Down's syndrome as well as for the treatment of schizophrenia and myoclonus [21].…”

Efficient synthesis of 4H-pyran derivatives using a polymeric catalyst based on PVP

“…pyrans and their derivatives are important class of heterocyclic compounds which have attracted the attention of chemists because of their wide range of useful biological and pharmacological properties, such as antitumor, anticancer, antibacterial, antioxidant, diuretic, and ant allergic [1][2][3][4] activities. These compounds can be used as pigments, fluorescence markers, photoactive of the prepared reagent showed that the attributed structure by Chehardoli is incorrect and the reagent is not protected at N-atom and is actually protonated at O-atom.…”

Insights into the Reaction Mechanism of the Tetrahydrobenzo [b] pyran by means of Kinetic Studies in the Presence of Fructose as a Green Catalyst

“…An important source with various applications in biology, pharmacology and diseases therapy is 4H-Pyran nucleus. These compounds are also employed in industrial and biodegradable agrochemicals [13][14][15][16][17][18][19][20][21][22] . Organic chemists encouraged to develop efficiencies and procedures for synthesis of these kinds of compounds [23][24][25][26] .…”