Liquid crystal monomers (LCMs) are biphenyl-or cyclohexane-based organic chemicals used in electronic digital displays, and several of them possess bioaccumulative and toxic properties. Little is known about their occurrence in indoor dust from the United States. We analyzed 60 LCMs in 104 residential indoor dust samples collected from 16 states across the United States. Forty-seven of 60 LCMs were detected in dust samples at a median ∑LCM concentration of 402 ng/g (range: not detected to 4300 ng/g). Trans-4-propylcyclohexyl trans,trans-4′-propylbicyclohexyl-4-carboxylate (MPVBC) and (trans,trans)-4-fluorophenyl 4′-pentyl-[1,1′-bi-(cyclohexane)]-4-carboxylate (FPeBC) were frequently detected in dust samples. We investigated potential sources of LCMs in dust by determining concentrations and profiles of these chemicals in smartphone screens, desktop and laptop computer monitors, and displays of other electronic devices and found that profiles in smartphones matched closely with those found in dust. The calculated median daily intake of ∑LCM through dust ingestion was 1.19 ng/kg bw/d for children, whereas that through dermal absorption was 0.18 ng/kg bw/d for adults in the United States.