Synthesis of Citronellol-Derived Antibacterial Polymers and Effect of Thioether, Sulfoxide, Sulfone, and Ether Functional Groups on Their Bactericidal Activity

Abstract

Citronellol-derived methacrylate polymers with four side chain interconnecting groups of different polarities (PCHM-Xs) are synthesized to prepare bio-based bactericidal polymers. The PCHM-X bactericidal activities are significantly affected by the different functional groups determining the interaction between the polymer chain and bacterial membrane that disrupts the membrane integrity causing cytoplasmic leakage, the main contributor to the polymer antibacterial properties. PCHM-SO, with a large dipole moment and strong hydrogen bonding ability, shows the best bactericidal activity among PCHM-Xs due to the strongest interactions with the bacterial membrane components. A sulfoxide-group-containing polymer with excellent bactericidal activity (99.99%) and the systematic study of the effect of different functional groups on the bactericidal activity are first reported herein.

Design of functional isocyanate-free poly(oxazolidone)s under mild conditions

“…All POxa were characterized by the presence of thioether linkages within their backbone, offering multiple possibilities for further modifications, notably by oxidation to sulfoxide or sulfone as well as by alkylation to sulfonium. 36,44 The polymer P2b was selected as a representative polymer for all post-polymerization modifications.…”

Development and Application of Intelligent Coating Technology: A Review

“…Titanium dioxide utilizes ultraviolet radiation to decompose organic substances in the air, producing oxides and free radicals, thereby achieving the effects of sterilization, deodorization, and air purification [84]. In order to improve the effectiveness of antibacterial coatings, scientists have collected and analyzed a large amount of data to effectively identify the antibacterial components that have the best bactericidal effect, thereby improving the bactericidal effect of intelligent antibacterial coatings [85]. In addition, the preparation of intelligent antibacterial coatings is also an important part of research and development.…”