VIII Information School of a Young Scientist Central Scientific Library of the Urals Branch of the Russian Academy of Science 2020
DOI: 10.32460/ishmu-2020-8-0009
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Synthesis of biological active compounds based on trifluoromethylcontaining 4-nitrosopyrazoles

Abstract: e-pot nitrosation of 1,3-diketones or their lithium salts followed by treatment of hydrazines. Reduction of the nitroso-derivatives made it possible to obtain the 4-amino-3-trifluoromethylpyrazoles chlorides. Cytotoxic activity of the compounds wase evaluated in vitro

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