Synthesis of Bibenzyl Derivatives via Visible-Light-Promoted 1,5-Hydrogen Atom Transfer/Radical Coupling Reactions of N-Fluorocarboxamides

Visible-light-induced tandem ring opening/1,6-conjugate addition of cyclobutanols with p-quinone methides under metal- and additive-free conditions

“…Thus, the development of a general and “greener” methodology in the construction of γ,γ- and δ,δ-diaryl ketones via ring-opening 1,6-conjugate addition is highly desirable. As part of our continued interest in photoredox catalysis, 13 we herein developed an eco-friendly visible-light-induced tandem ring opening/1,6-conjugate addition of readily accessible cyclobutanols with p -QMs, which gives various δ,δ-diaryl ketones in good yields (Scheme 1d). Importantly, our method employs visible light as the energy input and the reaction occurs under metal- and additive-free conditions at room temperature.…”