Synthesis of benzothienopyridopyrimidinones and benzothienopyrimidoisoquinolinone by microwave-assisted dehydrogenation of the corresponding tetrahydro derivatives

Abstract

DDQ was employed as a dehydrogenation reagent to synthesize polyaromatic compounds from the corresponding tetrahydro derivatives. A microwave-assisted process allows shorter reaction times and easier purification as fewer degradation products were formed.