Synthesis of AuPt/graphene quantum dots nanocomposites for determination of glucose by photoluminescence spectroscopy

Viet, Thieu Quang Quoc; Thanh, Huynh Phuoc; Khoi, Do Minh; Thi Kieu Trinh, Tran; My, Ngo Nguyen Tra; Pham, Toan Duy; Vu Thanh, Luong Huynh; Tran-Nguyen, Phuong Lan; Quyen, Tran Thi Bich

doi:10.1039/d3nj00300k

Cited by 5 publications

(4 citation statements)

References 51 publications

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“…The peaks are typical for C-H, C-O-C, and C = O in GQDs corresponding to 2844 cm − 1 , 1610 cm − 1 , 1198 cm − 1 , have moved to 2984 cm − 1 , 1636 cm − 1 , 1398 cm − 1 , respectively. Since the IR absorbance of Au and Pt nanocrystals ranges from 600 cm − 1 to 4000 cm − 1 , the strong interaction between GQDs and both Au and Pt nanocrystals can be considered as the cause of the changes in the FTIR spectra of AuPt/GQDs (Viet et al 2023). As a result, the FTIR results above reveal the presence of AuPt NCBs in GQDs and the successful synthesis of AuPt NCBs/GQDs.…”

Section: Resultsmentioning

confidence: 99%

Novel synthesis of AuPt bimetallic nanocubes combined with graphene quantum dots for non-enzymatic sensor of glucose determination by electrochemical method

Tran,

Phan,

Nguyen

et al. 2023

Preprint

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In this study, AuPt bimetallic nanocubes (AuPt NCBs) were successfully combined with graphene quantum dots (GQDs) by a simple and easy-to-implement method at 80oC for 90 min. In particular, graphene quantum dots (GQDs) nanoparticles were synthesized by hydrothermal method at 190oC for 8 h, using raw materials from wheat flour, which are environmentally friendly materials, available and abundant in nature. AuPt bimetallic nanocubes were obtained from the synthesis of Au nanocubes (Au NCBs), followed by AuPt nanoparticles obtained when reacted at 140oC for 2 h by hydrothermal method to form AuPt core/shell nanocubes (AuPt NCBs). Besides, the synthesized AuPt NCBs/GQDs nanocomposites were also characterized, shape, size and composition by: UV-vis, FTIR, XRD, TEM, EDX, XPS, and AFM. The obtained results show that the Au nanocubes (Au NCBs) have an average particle size of ~ 39 nm; the size of AuPt NCBs and GQDs nanoparticles are ~ 40–44 nm and ~ 3–5 nm in size, respectively. Furthermore, AuPt NCBs/GQDs nanocomposites are also used as non-enzymatic catalysts for the oxidation/reduction of glucose by cyclic voltammetry (CV). The obtained results indicate that the AuPt NCBs/GQDs nanocomposites with high catalytic activity are capable of detecting glucose in a wide concentration range from 10− 12 M to 1 M, with an extremely low limit of detection (LOD) of concentration glucose levels (~ 10− 12 M). Therefore, AuPt NCBs/GQDs are novel and promising nano-catalysts that can be applied as catalysts with high activity oriented to many fields such as environmental treatment, fuel energy cells, or sensors to make bio-chip devices for early diagnosis of serious diseases such as diabetes, gout or cancer, etc., in present and the future.

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Section: Resultsmentioning

confidence: 99%

Novel synthesis of AuPt bimetallic nanocubes combined with graphene quantum dots for non-enzymatic sensor of glucose determination by electrochemical method

Tran,

Phan,

Nguyen

et al. 2023

Preprint

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“…The preparation of AuPt@GQDs core−shell nanocomposites was done as per the newly reported methodology of Viet et al, with some modifications. 50 Briefly, different amounts of AuPt dispersion (0.01, 0.05, and 0.1 mg/mL) (2.5 mL) were mixed with 7.5 mL of GQDs (0.05 mg/mL) using probe sonication (220 kHz, 3 h). The dark brown liquid was isolated using centrifugation at (5000 rpm, 10 min) and dialysis (MWCO-3.5 kDa, 12 h), followed by overnight drying to get AuPt@GQDs core−shell nanocomposites.…”

Section: Methodsmentioning

confidence: 99%

“…The preparation of AuPt@GQDs core–shell nanocomposites was done as per the newly reported methodology of Viet et al, with some modifications . Briefly, different amounts of AuPt dispersion (0.01, 0.05, and 0.1 mg/mL) (2.5 mL) were mixed with 7.5 mL of GQDs (0.05 mg/mL) using probe sonication (220 kHz, 3 h).…”

Section: Methodsmentioning

confidence: 99%

“…Besides, the localization of exposed surface groups like COOH and OH in GQDs also contributes to improving its solubility and provides better control over the metallization process through surface grafting . Until now, only a few reports have been available that show surface engineering of AuPt core–shell NPs using GQDs or carbon quantum dots (CQDs). − However, the major drawback with these methods is their operational complexities, such as the use of expensive reagents and extreme temperatures. Thus, to achieve ease in fabrication, we selected a green reducing agent and probe sonication method to synthesize our GQD-functionalized AuPt core–shell nanocomposites, which show better dispersibility and good electrical properties.…”

Section: Introductionmentioning

confidence: 99%

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Fabrication of a Label-Free Immunosensor Using Surface-Engineered AuPt@GQD Core–Shell Nanocomposite for the Selective Detection of Trace Levels of Escherichia coli from Contaminated Food Samples

Das,

2024

ACS Biomater. Sci. Eng.

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Fabrication of label-free immunosensors is highly necessitated due to their simplicity, cost-effectiveness, and robustness. Herein, we report the facile development of a label-free, direct, rapid, capacitive immunosensor for ultrasensitive and rapid recognition of trace levels of Escherichia coli from contaminated food samples. This was achieved using gold platinum core–shell nanoparticles loaded with graphene quantum dots (AuPt@GQDs) that were utilized as electrode modifiers. The incorporation of GQDs to the surface of AuPt core–shell nanoparticles was performed using the “greener” probe-sonication method. The electrochemical properties of AuPt@GQDs, determined using cyclic voltammetry and electrochemical impedance spectroscopy, suggested the optimized loading concentration of AuPt to be 0.05% in the core–shell nanocomposite to exhibit the highest current response. Furthermore, immobilization of anti-E. coli monoclonal antibodies (anti-E. coli mAb) onto the surface of modified electrodes was performed using amine coupling. The high specific binding of E. coli cells onto the surface of the immuno-electrode was measured as a direct function of change in transient capacitance with time that was measured at low and high frequencies. The resultant immunosensor (bovine serum albumin/anti-E. coli mAb/AuPt0.05@GQDs/FTO) demonstrated a detection range (5 to 4.5 × 103 cells/mL), with the detection limit as low as 1.5 × 102 cells/mL, and an excellent sensitivity ∼171,281.40 μF–1 mL cells–1 cm–2 without the use of any labels (R 2-0.99). These findings were further verified using real sample analysis wherein the immuno-electrode demonstrated outstanding sensitivity, the highest noticed so far. More interestingly, the high resuability ∼48 weeks (RSD-5.92%) and excellent reproducibility in detection results (RSD ∼ 9.5%) testify its potential use in a clinical setting. The results reveal the usefulness of the surface-engineered AuPt@GQDs core–shell nanocomposite as an electrode modifier that can be used for the development of newer on-site monitoring devices to estimate trace levels of pathogens present as contaminants in food samples.

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Novel synthesis of AuPt bimetallic nanocubes combined with graphene quantum dots for non-enzymatic sensor of glucose determination by electrochemical method

Quyen,

Trang,

Huynh

et al. 2023

Chem. Pap.

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Synthesis of AuPt/graphene quantum dots nanocomposites for determination of glucose by photoluminescence spectroscopy

Abstract: In this study, a novel material, AuPt/graphene quantum dot nanocomposites (AuPt/GQDs NCPs), that have unique optical properties were successfully synthesized.

Cited by 5 publications

References 51 publications

Novel synthesis of AuPt bimetallic nanocubes combined with graphene quantum dots for non-enzymatic sensor of glucose determination by electrochemical method

Novel synthesis of AuPt bimetallic nanocubes combined with graphene quantum dots for non-enzymatic sensor of glucose determination by electrochemical method

Fabrication of a Label-Free Immunosensor Using Surface-Engineered AuPt@GQD Core–Shell Nanocomposite for the Selective Detection of Trace Levels of Escherichia coli from Contaminated Food Samples

Novel synthesis of AuPt bimetallic nanocubes combined with graphene quantum dots for non-enzymatic sensor of glucose determination by electrochemical method

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