Synthesis of Arylfurans by Organic‐Solvent‐Free Method Using Phosphoric Acid as a Solvent and Catalyst

Abstract

Phosphoric acid when being used as a solvent readily catalysed the cyclization reaction of 1,4-dicarbonyl compounds to furnish a broad range of arylfuran compounds using the Paal-Knorr furan synthetic method. The advantages of this synthetic method include an organic-solvent-free system, cheap and recyclable catalyst, easy experimental setup under air, short reaction time, wide substrate scope, broad functional group tolerance, eminent atom economy and excellent yields. The recovered acidic catalyst could be reused many times without significant loss in the catalytic activity. The photophysical properties of some selected arylfurans were examined in dilute solution. We found that most of the arylfurans emit in deep blue or violet region with moderate to high absolute quantum yields.

Synthesis of Chalcones: An Improved High-Yield and Substituent-Independent Protocol for an Old Structure

“…Consequently, in this case, it was necessary to change the reaction conditions and carry out the reaction at room temperature, using reaction conditions similar to those described in the literature [30], to obtain a reasonable yield. In any case, the corresponding Wittig reaction between 3{5} and the corresponding ylide 9{1} afforded the chalcone 1{1,5} in 95% yield and high purity, once more showing the better performance of this protocol.…”