Synthesis of Amphiphilic Miktoarm ABC Star Copolymers by RAFT Mechanism Using Maleic Anhydride as Linking Agent

Abstract

The preparation and characterization of amphiphilic ABC miktoarm star copolymers based on polystyrene, and poly(ethylene oxide), poly(methyl acrylate) or poly(N-isopropylacrylamide) blocks are described in this paper. First, macrotransfer agent polySt-MAh-S-C(S)Ph with maleic anhydride and a dithio group at one end of polymer chain was synthesized by the reaction of a dithio group at the end of the polystyrene with maleic anhydride (MAh) in tetrahydrofuran solution. The second, reversible additionfragmentation chain transfer polymerization of methyl acrylate or N-isopropylacrylamide was carried out in the prescence of polySt-MAh-S-C(S)Ph and benzoyl peroxide. Finally, the anhydride group at the joint of two blocks was reacted with terminal hydroxyl group of poly(ethylene glycol methyl ether). The obtained ABC star copolymers were characterized by 1 H NMR spectroscopy and gel permeation chromatography.

Preparation of Star‐Shaped ABC Copolymers of Polystyrene‐Poly(ethylene oxide)‐Polyglycidol Using Ethoxyethyl Glycidyl Ether as the Cap Molecule

“…a multifunctional small molecule as initiator [11] and; (d) a multifunctional macroinitiator strategy by cap molecules. [12][13][14] In the literature, the PS and PEO chains were always used as arms of star-shaped copolymers because of their typical hydrophobicity and hydrophilicity. [15] The polyglycidol (PG) derived from poly(ethoxyethyl glycidyl ether) (PEEGE) is another kind of polyoxirane with a primary hydroxyl group on each repeat unit which could also be further chemically modified.…”

Synthesis of amphiphilic and thermoresponsive ABC miktoarm star terpolymer via a combination of consecutive click reactions and atom transfer radical polymerization

“…[5][6][7][8][9][10][11][12][13] With the advent of controlled radical polymerizations, such as nitroxide-mediated radical polymerization (NMP), atom transfer radical polymerization (ATRP), and reversible addition-fragmentation chain transfer (RAFT) polymerization, the once challenging task of synthesizing ABC Correspondence to: S. Liu (E-mail: sliu@ustc.edu.cn) miktoarm star polymers has been rendered much easier. [14][15][16][17][18][19] Feng and Pan 14 successful prepared ABC miktoarm star terpolymers consisting of polystyrene (PS), poly(methyl acrylate) (PMA), and poly(ethylene glycol) (PEG) via successive RAFT polymerization of styrene, maleic anhydride (MAh), and methyl acrylate, followed by the esterification reaction with monohydroxyl-terminated PEG. This strategy takes advantage of MAh's inability to homopolymerize during the RAFT process, and only one MAh unit is incorporated at the diblock junction point.…”

Synthesis of an ABCD 4-Miktoarm Star Quaterpolymer Through a Diels–Alder Click Reaction

“…Other less common structures like AB 5 , AB 2 C 2 and ABCD are now also accessible [2][3][4][5][6]. Recently, diverse methods have been reported for the preparation of miktoarm star polymers, ranging from the combinations of the controlled/living radical polymerization systems (atom transfer radical polymerization (ATRP), nitroxide mediated radical polymerization (NMP) and reversible addition fragmentation chain transfer (RAFT) polymerization), to the combinations of them with other living polymerization (LP) methods (e.g., ring-opening polymerization (ROP)) [7][8][9][10][11][12][13][14][15][16][17][18][19]. These methods gave rise to a variety of miktoarm stars like AB 2 , A 3 B 3 , A(BC) 2 and ABC.…”