Synthesis of Amino‐1,2‐dihydro‐1‐pyrrolizinones.

Abstract

Fused pyrrole derivatives Fused pyrrole derivatives R 0160Synthesis of Amino-1,2-dihydro-1-pyrrolizinones. -Three isomers of title compounds [cf. (VIII)] are prepared by reduction of the corresponding nitropyrrolizinones (V)-(VII). Some N-acylated derivatives of (VIII) such as compounds (IX) show significant analgesic and/or anti-inflammatory activities. -(YANG*