Synthesis of Air‐Stable Cyclopentadienyl Fe(CO)₂ (Fp) Polymers by a Host–Guest Interaction of Cyclodextrin with Air‐Sensitive Fp Pendant Groups

Abstract

Host-guest chemistry is used to address the challenge of the synthesis of air-stable polymers containing air-sensitive metal complexes. The complexation of the CpFe(CO) (Fp) pendent group with cyclodextrin (CD) molecules created air-stable poly(Fp-methylstyrene) P(CD/FpMSt). This CD complexation resulted in dimerization of the adjacent Fp groups, which was characterized by NMR, FTIR, and cyclic voltammetry (CV) analyses. P(CD/FpMSt) was soluble in DMSO and remained stable even the solution was exposed to air for months. The host-guest chemistry accounted for the improved stability, because the Fp groups decomposed upon removal of the CD molecules using competing guest molecules. The CD-complexed polymer showed light-trigged properties, including CO release and antimicrobial activity. Host-guest chemistry of air-sensitive organometallic complexes is therefore a promising technique that can be used to broaden the scope of metal-containing polymers (MCPs) with processable novel functions.

Photo‐Degradable Micelles Capable of Releasing of Carbon Monoxide under Visible Light Irradiation

“…[23,24] To further improve the stability and bioavailability of CORMs, COreleasing polymers have been developed through the incorporation of small molecule CORMs into polymeric matrices through either post-modification or direct polymerization approaches. [25][26][27][28][29][30] Despite increased stability and bioavailability as compared to the small molecule precursors, these COreleasing polymers typically suffered from spontaneous CO release. [24,31] To address this problem, we recently developed a CO-releasing polymer that can selectively release CO under visible light irradiation by the introduction of 3-hydroxyflavone (3-HF) derivatives.…”

Macrocycles-assisted polymeric self-assemblies fabricated by host–guest complexation and their applications

“…The anticancer efficiency of this nanomedicine was increased as compared to that of the currently available (Taxol), playing a vital role in cancer treatment. A thermoresponsive supramolecular system was constructed by Zhu et al 77 Wang et al 79 developed an alternative approach for the preparation of an air-stable supramolecular complex (solid/solution) through the complexation of the air-sensitive CpFe(CO) 2 (Fb) pendant-containing polymer (G9) with b-CD. The formed b-CD@G9 complex produced an intramolecular dimerization with the nearby Fp pendant, exhibiting improved stability (Fig.…”

β-Cyclodextrin-Calcium Complex Intercalated Hydrotalcites as Efficient Catalyst for Transesterification of Glycerol

“…β-CD was widely used and studied because of its moderate cavity size, excellent physicochemical properties and relatively low price [8,9]. Cyclodextrin derivatives and their composite with different materials greatly expanded the application of cyclodextrin in different fields [10].…”