Synthesis of a stable indium complex derived from γ-silyl-α,α-difluorobromopropyne: evaluation of experimental parameters

Nucleophilic and electrophilic substitutions of difluoropropargyl bromides

“…We surmised that this high yield was associated with the distinctive properties of the TIPS group [19]. Similar results were obtained with other bulky silyl substituents [20]. However, with R = TMS the yield was disappointingly low (19%) under the same conditions.…”

Crystallographic Characterization of Difluoropropargyl Indium Bromide, a Reactive Fluoroorganometallic Reagent

“…Earlier, we had reported that the reaction of a silylfluoropropargyl bromide 1 with indium in predominantly aqueous media produced a stable complex, which is loosely represented as 2 (Scheme 1) 6. The organoindium compound 2 yielded 3 or 4 , depending on the nature of the electrophile (E) used 7.…”