Synthesis of a nitro complex of RuIII(salen): Unexpected aromatic ring nitration by a nitrite salt

Ruthenium(III) Cyclometalates Obtained by Site‐Specific Orthometallation and Their Reactivity with Nitric Oxide: Photoinduced Release and Estimation of NO Liberated from the Ruthenium Nitrosyl Complexes

“…The sites for nitration were different in the two cases; this occurs because the preferred para position (with respect to the phenolato function) [22] for nitration was blocked by the methyl group in complex 2a. However, for complex 2a the oxidative cyclization and formation of the benzoxazole derivative showed a rare type of reactivity of NO with this family of complexes (vide infra).…”

Regiospecific Synthesis of Nitroarenes by Palladium‐Catalyzed Nitrogen‐Donor‐Directed Aromatic CH Nitration

“…The reaction exhibited a primary kinetic isotope effect both in the intramolecular ( k H / k D =5.3) and intermolecular ( k H / k D =4.6) competition experiments, consistent with a rate‐determining cyclopalladation step. When the reaction was performed under the standard conditions in the presence of TEMPO (2.0 equiv), a radical scavenger,18 the reaction failed to give any nitrated products, supporting a silver‐mediated radical mechanism11a, 19, 20 involving palladium(II/III)13b–c and/or palladium(II/IV)13a, 21 catalytic cycles under oxidizing conditions (Scheme ) 13d–e…”

Nitric oxide release from a photoactive water-soluble ruthenium nitrosyl. Biological effects

“…This specificity may minimize systemic side-effects while controlling the timing of such an event [2][3][4][5][6]. In this context, we [7][8][9][10][11][12][13][14] and others [15][16][17][18][19][20][21][22][23][24][25][26][27] have studied the photochemistry of ruthenium nitrosyl compounds owing to their thermal stability and their photolability toward NO release. Endogenously produced NO demonstrates key bioregulator roles in mammalian physiology (including vasodilation) [28] as well as serving as a cyto-toxin at the higher concentrations generated during immune response to pathogens [29][30][31].…”