“…At the present time, the ultimate extension of this procedure is Asperger's ligand LDDL, N,N'-bis(2-amino-3(S)-phenylpropyl)-truns-l(R), 2(R)-cyclohexanediamine, designed with four sterically demanding asymmetric centers. Though a study of scaled molecular models suggested that only the A-s-cis isomer should exist, only the trans isomer has been found (27).…”