Synthesis of a nano molecularly imprinted polymeric sorbent for solid phase extraction and determination of phenytoin in plasma, urine, and wastewater by HPLC

Abstract

In this work a nano polymeric sorbent for phenytoin was synthesized by non-covalent molecularly imprinted polymerization approach.

Fabrication of a surface molecularly imprinted polymer membrane based on a single template and its application in the separation and extraction of phenytoin, phenobarbital and lamotrigine

“…Furthermore, the proposed method was compared with some other available methods based on MIPs or membrane extraction in the literature for PHT, PHB, and/or LTG. 28–33,47–53 As shown in Table 6, the extraction recovery of the current method for PHT in plasma was similar with that in the works by Jia's group 28 and Yaripour's group 33 but higher than that in other methods. 47,48,53 The extraction recovery of the current work for PHT in aqueous solution was obviously higher than that in the reference methods.…”

“…28–33,47–53 As shown in Table 6, the extraction recovery of the current method for PHT in plasma was similar with that in the works by Jia's group 28 and Yaripour's group 33 but higher than that in other methods. 47,48,53 The extraction recovery of the current work for PHT in aqueous solution was obviously higher than that in the reference methods. 47,52 In the case of PHB, the extraction recovery in the current work for plasma was higher than that of the reported methods, 50,53 while the extraction recovery in current work for aqueous solution was higher than that of MIPs or electromembrane extraction 49,52,53 but similar with that of MIP fiber extraction, 29 which may result from the similar characters between MIP fiber and MIPMs.…”

“…47,48,53 The extraction recovery of the current work for PHT in aqueous solution was obviously higher than that in the reference methods. 47,52 In the case of PHB, the extraction recovery in the current work for plasma was higher than that of the reported methods, 50,53 while the extraction recovery in current work for aqueous solution was higher than that of MIPs or electromembrane extraction 49,52,53 but similar with that of MIP fiber extraction, 29 which may result from the similar characters between MIP fiber and MIPMs. In the case of LTG, the extraction recovery of the employed method for plasma or aqueous solution was lower than that of previous works based on MIPs, 30–32,51 which may result from the different templates used to prepare the MIPs.…”

Facile preparation of magnetic molecularly imprinted polymers for the selective extraction and determination of dexamethasone in skincare cosmetics using HPLC

“…Moreover, the introduction of magnetic nanoparticles into MIPs field has greatly expanded the application of MIPs in sample preparation. For example, magnetic nanoparticles are usually coated by imprinted polymer layers to fabricate magnetic MIPs, in which the polymer layers not only protect the magnetic nanoparticles against aggregation but also endow high selectivity of magnetic nanoparticles for target molecules [24]. Liu et al have synthesized magnetic MIPs for separation hydrocortisone and dexamethasone from cosmetic samples [25].…”