Synthesis of a fused <i>N</i>-bridged [3.3.1]nonadiquinoline multicyclic skeleton <i>via</i> a metal-free formal [4 + 2] cycloaddition/Mannich/dearomatization domino reaction

Amiri, Kamran; Nayebzadeh, Behrouz; Kamangar, Mohammad; Babazadeh, Mohammad; Ariafard, Alireza; Shiri, Farshad; Rominger, Frank; Balalaie, Saeed

doi:10.1039/d3gc03026a

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Six-membered Ring Fused With Quinolines1

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2024

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“…Mechanistically, zinc plays a vital role for the purpose of facilitation formal An inventive pathway reported in Balalaie group used bifunctional property of enolized-o-alkynylquinoline carbaldehydes 272 for the synthesis of hydroacridine-fused quinolines 273 (Scheme 87). [176]…”

Section: Six-membered Ring Fused With Quinolinesmentioning

confidence: 99%

Recent Advances in the Synthesis of Fused‐Cyclic Quinolines

Darbandizadeh,

Balalaie

2024

Asian J Org Chem

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Fused quinolines have gained substantial attention due to their significant biological and wide‐spectrum synthetic applications. This review supplies an encyclopedic document regarding the approaches developed for the synthesis of fused‐cyclic quinolines based on ring volume size reported thus far. This collected information will be valuable for medicinal chemists to obtain knowledge regarding designing new approaches in order to access biological active compounds.

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Section: Six-membered Ring Fused With Quinolinesmentioning

confidence: 99%