Synthesis of 8-R-9c-alkyl-1-aryl-2-benzyl-1-hydroxy-1,2,9b,9c-tetrahydro-5-oxa-2-aza-cyclopenta[2,3]cyclopropa[1,2-a]naphthalene-3,4-diones and reaction thereof with acetic anhydride

Syntheses and Biological Activities of Chroman-2-ones. A Review

“…Shchepin et al 98 2-benzyl-1-hydroxy-1,2,9b,9c-tetrahydro-5-oxa-2-aza-cyclopenta [2,3]cyclopropa[1,2-a] naphthalene-3,4-diones 106; the acylation of these compounds occurred via an unexpected rearrangement to give 4 -alkyl-5 -aryl-1 -benzyl-3,4,2 ,3 -tetrahydro-2,2 -dioxospiro[chroman-3,3 -pyrrol]-4-yl acetates 107 (Scheme 28).…”

Aqua mediated synthesis of 2-amino-6-benzothiazol-2-ylsulfanyl-chromenes and its in vitro study, explanation of the structure–activity relationships (SARs) as antibacterial agent

“…So, the judicious use of antibacterial agent is an important approach in an attempt to control the emergence of bacterial resistance. In order to discover more potent inhibitors, we have successfully attempted a novel and green synthesis of benzothiazol-2-ylsulfanyl-chromenes through substitution of chromenes with 2-Benzothiazolethiol [15].…”