Synthesis of 7‐{[2‐(4‐ substituted phenyl)‐2‐oxoethyl] amino}‐4‐methyl‐2H‐1‐benzopyran‐2‐one derivatives and evaluation of their pharmacological activities
G. V. Megha,
Yadav. D. Bodke
Abstract:In this study, a novel series of 7‐[2‐(4‐substituted)‐2‐oxoethyl]amino‐4‐methyl‐2H‐1‐benzopyran‐2‐one derivatives (3 a‐f) were synthesized using 7‐amino‐4‐methyl coumarin and p‐substituted phenacyl bromides, and their pharmacological effects were examined. This reaction was carried out with potassium carbonate as a catalyst in dimethylformamide for 24 h at ambient temperature. The structures of synthesized compounds have been characterized by analysis using FTIR, NMR (1H and 13C) and Mass spectroscopic techniq… Show more
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