Synthesis of 6,8-substituted 4-(hydroxyphenylamino)- and 4-(aminophenylamino)-2-methylquinolines

Antimicrobial Activity of Quinoline-Based Hydroxyphenylamino and Carboxyphenylamino Derivatives

“…Synthesis. Experimental details for the synthesis could be found in the previously published work [34,35].…”

“…Quinoline derivatives used in this study were synthesized as previously describe [34,35]. Briefly, nucleophilic substitution of benz-substituted 4-chloro-2--methylquinolines with o-, m-, p-aminophenols and 2-and 4-aminobenzoic acids were done.…”

Synthesis and transformations of novel formyl-substituted quinolines

“…The 1 H and 13 C NMR spectra were recorded on a Varian Mercury 300Vx spectrometer at 300 MHz ( 1 H) and 75 MHz ( 13 C) with TMS as an internal standard. Substrates 1a -c (Reynolds et al , 1955 ) and 2a -c (Avetisyan et al , 2007 ) were prepared by known methods.…”

Dibenzonaphthyridinones: Heterocycle-to-Heterocycle Synthetic Strategies and Photophysical Studies

“…3 In an extension of this initial finding, we now show that 3,5-bis- o -nitrophenyl substituted isoxazole reduction in the presence of an added ketone can deliver dibenzonaphthyridinones (DBNs, Scheme 1b). Furthermore, while others have studied the optical properties of DBNs (and related structures), 4 we present new synthetic methodology for constructing these highly fluorescent and solvatochromic materials as well as experimental and theoretical exploration of their optical properties.…”