Synthesis of 3-n-butyltetrahydrophthalides

Cocker, Wesley; Sainsbury, D. M.

doi:10.1039/c19650000479

Cited by 2 publications

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“…Many of the reported syntheses were either in support of structure determination or to provide increased quantities of phthalides for bioactivity testing. The following are compounds synthesized and their corresponding references: compound 1 , , 5 , , 7 , 8 , − 9 , 11 , ,− 20 , − 34 , ,, 35 , − 36 , 37 , 56 , 60 , 64 , , 68 , and 69…”

Section: Structural Diversity Of Naturally Occurring Phthalide Deriva...mentioning

confidence: 99%

The Structural Diversity of Phthalides from the Apiaceae

2007

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Phthalides, and their corresponding dihydro and tetrahydro analogues, are components of several genera of the plant family Apiaceae. These taxa have been reported as exhibiting a wide range of bioactivities against experimental models of several illnesses and physiological conditions, including microbial and viral infections, stroke, tuberculosis, and vasoconstriction. Many of these genera are purported to possess medicinal values, and of these several are considered to be traditional herbal medicines. This review provides an overview of the methods of investigation, the structural diversity, and the bioactivity of phthalides, dihydrophthalides, tetrahydrophthalides, and dimers from plants in the Apiaceae.

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Section: Structural Diversity Of Naturally Occurring Phthalide Deriva...mentioning

confidence: 99%

The Structural Diversity of Phthalides from the Apiaceae

2007

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“…It is debatable. Though situations such as those in Cocker 134 would have inevitably benefited (and relieved the husband the awful task), it is questionable in others such as Inglis and Knight, where the victim may have been unable to communicate their wishes. Regardless of this, a positive effect in even a small number of cases would be advantageous, but this seems a very unlikely prospect and certainly no solution for cases like Knight's.…”

Section: Assisted Suicidementioning

confidence: 99%

Mercy Killing, Partial Defences and Charge Decisions: 50 Shades of Grey

Clough

2020

The Journal of Criminal Law

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The revolution of the partial defences to murder by the Coroners and Justice Act 2009 may have had a catastrophic impact on cases of mercy killing.1 While previously shoehorned into the diminished responsibility plea, the medicalisation of this defence may prevent such a ploy. However, a recent case has offered insight into the circumstances which may still result in a manslaughter conviction for mercy killers through a new avenue previously thought impermissible. This article will discuss the case and those similar, alongside charging decisions and just results. Mercy killing remains a grey area in the criminal justice system, but is there light at the end of the tunnel?

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Synthesis of 3-n-butyltetrahydrophthalides

Cited by 2 publications

References 0 publications

The Structural Diversity of Phthalides from the Apiaceae

The Structural Diversity of Phthalides from the Apiaceae

Mercy Killing, Partial Defences and Charge Decisions: 50 Shades of Grey

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