Synthesis of 3‐Alkyl‐5‐hydroxycyclohex‐2‐enones via Aldolic Addition/Sulfinate Elimination Tandem Reactions.

Abstract

Cyclohexane derivativesCyclohexane derivatives Q 0040 Synthesis of 3-Alkyl-5-hydroxycyclohex-2-enones via Aldolic Addition/Sulfinate Elimination Tandem Reactions. -In connection with a work on the synthesis of constituents of Bryophyte [cf. prelunularin (IIIc)], a six-step preparation of previously unreported 5-hydro-3-alkyl substituted cyclohex-2-enones (IIIa) and (IIIb) is developed. -(PANDOLFI*, E.; COMAS, H.; Tetrahedron Lett. 44 (2003) 25, 4631-4633; Dep. Org. Chem., Fac. Chem., Univ. Rep., 11800 Montevideo, Urug.; Eng.) -Mais 38-052