Synthesis of 3-(5-Methylthiophen-2-yl)coumarins and Their Photochromic Dihetarylethene Derivatives

Abstract

Novel unsymmetrical di(thienyl)maleic acid anhydride, including coumarin moiety, has been designed and synthesized. Its photochromism study and fatigue resistance estimation are reported. Microwave‐assisted procedure has been successfully used for synthesis of 3‐(5‐methylthiophen‐2‐yl)coumarins.

An expedient synthesis of thienylacetic acids using the Willgerodt-Kindler reaction under PTC conditions

“…7 The basic methods used for the synthesis of these compounds are based on hydrolysis of the corresponding nitriles, 8 the reduction of ketoacids, 9 Arndt-Eistert 10 and Willgerodt-Kindler 11 reactions. The Willgerodt-Kindler reaction is usually applied for the preparation of (thio)amides, carboxylic acids, and heterocycles.…”