Synthesis of 2D Metal–Organic Nanosheets (MONs) by Liquid Phase Exfoliation: Applications in Effective Delivery of Antiulcer Drugs and Selective Adsorption and Removal of Cationic Dyes
Abstract:Nowadays, the fabrication of 2D metal−organic nanosheets (2D MONs) has entered the research arena fascinating researchers worldwide. However, a lack of efficient and facile methods has remained a bottleneck for the manufacturing of these 2D MONs. Herein, a 2D metal−organic framework (MOF), i.e., 2D Cu-MOF, was synthesized using a facile and convenient stirring method by using 4,4′-trimethylenedipyridine (TMDP) as an organic linker. The as-prepared MOF was characterized in detail and based on single crystal X-r… Show more
Background
Nanometal-organic frameworks (nano-MOFs), which exhibit distinctive features, such as controlled release mechanisms, stimuli-responsive behaviors, and sustained drug release profiles, have emerged as promising candidates for next-generation drug delivery systems.
Area covered
This review outlines the impact of nano-MOFs in biomedical applications, emphasizing their potential for targeted drug delivery through active strategies and their biocompatibility considerations.
Expert opinion
The versatility and tunability of nano-MOFs pave the way for personalized medicine, allowing tailored formulations to meet individual patient needs. Despite their transformative potential, challenges remain in terms of stability, toxicity assessment, and standardization. As nano-MOFs progress from laboratory research to clinical trials, they present a paradigm shift in drug delivery, offering precision medicine solutions through theranostic platforms. The future holds promise for the use of nano-MOFs to revolutionize drug delivery, ushering in an era of personalized and effective therapeutic interventions.
Background
Nanometal-organic frameworks (nano-MOFs), which exhibit distinctive features, such as controlled release mechanisms, stimuli-responsive behaviors, and sustained drug release profiles, have emerged as promising candidates for next-generation drug delivery systems.
Area covered
This review outlines the impact of nano-MOFs in biomedical applications, emphasizing their potential for targeted drug delivery through active strategies and their biocompatibility considerations.
Expert opinion
The versatility and tunability of nano-MOFs pave the way for personalized medicine, allowing tailored formulations to meet individual patient needs. Despite their transformative potential, challenges remain in terms of stability, toxicity assessment, and standardization. As nano-MOFs progress from laboratory research to clinical trials, they present a paradigm shift in drug delivery, offering precision medicine solutions through theranostic platforms. The future holds promise for the use of nano-MOFs to revolutionize drug delivery, ushering in an era of personalized and effective therapeutic interventions.
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