Synthesis of 2‐Pyridyl Based N(1)‐Substituted Thiosemicarbazonates of Nickel(II) as Bioactive Materials against MRSA, S. aureus, S. typhimurium 2, and K. pneumonia
Mani Kaushal,
Ritu Bala,
Tarlok S. Lobana
et al.
Abstract:In this investigation, the bio‐activity and biosafe potential of thiosemicarbazonates of nickel(II) as well as that of ligands are described. Reactions of nickel(II) acetate with a series of thiosemicarbazones, {R1(py)C2=N3‐N2(H)‐C1(=S)‐NHR; R1=py, Me, H and Ph; R=H, Me, Et, Ph}, led to the loss of acidic hydrazinic N2(H) protons, and resulted in the formation of six‐coordinated complexes of stoichiometry, [Ni(N,N,S−L)2], where anionic N,N,S−L=py2tsc‐NHR, 1–4; apytsc‐NHR, 5–8; pytsc‐NHR, 9–12 and bpytsc‐NHR, 1… Show more
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