Abstract:Quinazolin-4(3Н)-one derivatives are characterized by a wide range of pharmacological properties, among which the most significant one is a pronounced effect on the central nervous system. In this regard, a molecular design of biologically active compounds that have an analgesic activity due to the formation of ligand-receptor complexes with nociceptive and dopamine receptors, has been performed.The aim of the study was a molecular design and a subsequent targeted synthesis of 2-phenyl- and 2-benzyl derivative… Show more
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