“…Following reaction with benzylamine (C2) and 3,4-dimethoxybenzylamine (C3), products 2-(benzylamino)naphthalene-1,4-dione (C4) and 2-((3,4-dimethoxylbenzyl)amino) naphthalene-1,4-dione (C5) were afforded in 92 and 85% yields, respectively. Using a cyclization reaction previously reported by Lavrikova and coworkers, 28 completed in acetic acid, and following treatment with a mixture of nitric and sulfuric acids, 1-hydroxy-2-phenyl-1 H -naphtho[2,3- d ]imidazole-4,9-dione (C6) and 2-(3,4-dimethoxyphenyl)-1-hydroxy-1 H -naphtho[2,3- d ]imidazole-4,9-dione (C7) could be obtained in 67 and 84% yields, respectively. 1-Hydroxy-2-phenyl-1 H -naphtho[2,3- d ]imidazole-4,9-dione derivatives C6 and C7 were then esterified with different acid chlorides using triethylamine as the base, providing compounds 2–15 .…”