Synthesis of 2-Amino-5-Mercapto-1,3,4-Thiadiazole Derivatives and Evaluation of their Biological Activity

Abstract

In this work, new compounds, (S1-S17) were synthesized through the reaction of 5-amino-1,3,4thiadiazole-2-thiol with different aromatic aldehyde by using fusion method. The newly synthesized compounds were confirmed by FT-IR-spectra and 1 H-NMR, the biological activity of some new compound tested in vitro, against some bacterial positive and negative