Synthesis of 2‐amino‐4‐mercapto‐s‐triazine (5‐aza‐thiocytosine)

Abstract

2‐Amino‐4‐mercapto‐s‐triazine (IV), an analog of cytosine, has been prepared from cyanuric chloride by a three steps synthesis and by cyclisation of guanylthiourea with ethyl formate. The mass spectra of compounds III, IV and V have been investigated and fragmentation patterns are presented which account for most of the major ions. Preliminary biological tests are reported.