Synthesis of 2-alkyl substituted benzimidazoles under microwave irradiation: Anti-proliferative effect of some representative compounds on human histiocytic lymphoma cell U937

Simultaneous Voltammetric Determination of Theophylline and Guaifenesin Using a Multiwalled Carbon Nanotube‐Ionic Liquid Modified Glassy Carbon Electrode

“…2‐Propyl‐1 H ‐benzo[ d ]imidazole (3m): 16e The crude product was purified by column chromatography on silica gel (petroleum ether/ethyl acetate=2:1) to give 3m as a yellow liquid; yield: 42.3 mg (66%); R f =0.58 (PE/EA=2/1); 1 H NMR (400 MHz, CDCl 3 ): δ =9.51 (br s,1 H), 7.58–7.51 (m, 2 H), 7.24–7.22 (m, 2 H), 2.97 (t, J =7.2 Hz, 2 H), 1.97–1.88 (m, 2 H), 0.99 (t, J =7.2 Hz, 3 H); 13 C NMR (100 MHz, CDCl 3 ): δ =155.7, 138.7, 122.1, 114.6, 31.3, 21.8, 13.9.…”

The new threading system 2-benzyl-5,6-dimethyl-1H-benzo[d]imidazolium – dibenzo-24-crown-8: a model for Monte Carlo calculations incorporating an anion for the first time in threaded structures

“…(3) The general procedure for the formation of the salts 1$BF 4 : initially, the 2-benzyl-5,6-dimethyl-1H-benzoimidazole was prepared by the methodology developed in our laboratory. 11 Next, for the preparation of the salt, to 1.0 mmol of benzimidazole, 1.0 mmol of 45% aqueous uoroboric acid was added and stirred at room temperature for 5 minutes to get the corresponding salt. The salt was recrystallized from chloroform and dried under vacuum.…”

Alkyl-1h-Benzo[d]imidazole Synthesis From Alkyl Bromides and 1,2-Benzenediamines by a Mild Domino Reaction

“…Thermal decomposition of 2-azidobenzenamines in the presence of an aldehyde produces 2-alkyl-substituted benzimidazoles [20]. Green methods involving microwaves have also been used to synthesize 2-alkylbenzimidazole derivatives [21,22].…”