Synthesis of 2,3-dihydroquinazolin-4(1 H )-ones catalyzed by α -chymotrypsin

Fe3O4@Sap/Cu(ii): an efficient magnetically recoverable green nanocatalyst for the preparation of acridine and quinazoline derivatives in aqueous media at room temperature

“…To now, several methods have been reported for the one-pot multi-component condensation synthesis of acridine and quinazoline derivatives, 41 employing a wide variety of catalysts such as Fe 3 O 4 /HT-SMTU-Zn II , 42 SBA/AuNP, 43 [Nbdm][OH], 44 Co-aminobenzamid@Al-SBA-15, 45 α-chymotrypsin, 46 Pd(OAc) 2 , 47 KCC-1/Pr-SO 3 H, 48 and CuCl 2 , 49 Co–alanine complex, 50 magnetic praseodymium nanocatalyst, 51 nano-Fe 3 O 4 -DOPA-SnO 2 , 52 MNPs-NPB-SO 3 H, 53 SDS 54 and bentonite. 55 Despite the usefulness of these catalysts, they also have some limitations including high toxicity, use of expensive materials, complex synthetic processes, long reaction times, and sometimes low yields.…”

FeCl3/Egg shell: An Effective Catalytic System for the Synthesis of 2,3-Dihydroquinazolin-4(1H)-ones at Room Temperature

“…The all products prepared 3a-l are known compounds and characterized by comparing their 1 H NMR data with authentic samples reported in the literature (26)(27)(28)(29)(30).…”

Fast quinazolinone synthesis by combining enzymatic catalysis and photocatalysis

“…Consequently, the synthesis of quinazolinones using enzymatic catalysis has gained attention [29]. For example, Zhang et al [30] reported the synthesis of dihydroquinazolinone derivatives by efficiently catalyzing the condensation reactions of 2-aminobenzamide and a range of aldehydes with α-Chymotrypsin (Scheme 1, a). Compared to the traditional methods [19,21,26], this method had several advantages including its efficiency, high yield, and purity of the obtained products.…”