Synthesis of 1-functionalized pyrenes from 1-lithiopyrene, and their application as fluorescent probes for the components of the Ginkgo biloba L. leaves extract

Fluorescent Detection of 2,4‐DNT and 2,4,6‐TNT in Aqueous Media by Using Simple Water‐Soluble Pyrene Derivatives

“…As a first step, we have synthesized some simple water‐soluble pyrene derivatives (Scheme ), such as pyrene‐1‐carboxylic acid 1 and 1‐aminomethylpyrene 2 according to our previously reported approaches . 1‐Pyrenesulfonic acid 3 and 1‐aminopyrene 4 have been prepared as described…”

“…As af irst step, we have synthesized some simple water-soluble pyrene derivatives(Scheme 1), such as pyrene-1-carboxylic acid 1 and 1-aminomethylpyrene 2 according to our previously reported approaches. [30] 1-Pyrenesulfonic acid 3 and 1-aminopyrene 4 have been prepared as described. [31] In order to obtain water-soluble forms of compounds 1-4, the corresponding potassium (for 1,3)o rT FA salts (for 2,4) were prepared in situ.N ext, the photophysical properties of the probes 1-4 in aqueous solutions were investigated (Table 1, Figure 1).…”

“…The procedures for the synthesis of fluorophores 1-4 have been described previously. [30,31] Measurements and Characterizations 1 H( 400 MHz) and 13 CNMR (100 MHz) spectra were measured on aB ruker Avance-400 spectrometer.F luorescence spectra and fluorescence titration experiments were recorded on Horiba-Fluoromax-4 and Ocean Optics USB4000-FL spectrofluorometers. UV/Vis absorption spectra were recorded on aS himadzu UV-2550 spectrophotometer.…”

Highly Selective Fluorimetric Turn‐Off Detection of Copper(II) by Two Different Mechanisms in Calix[4]arene‐Based Chemosensors and Chemodosimeters

“…The novel 1‐pyrenebutanaldoxime, 3 , was required to access S2 whilst known 1‐pyrenecarbaldoxime was needed to prepare S1 , S3 and S4 . The aldehyde precursor to the latter was commercially available whilst 1‐pyrenebutanal was prepared from the acid following lithal reduction to the known alcohol (95 %) and pyridinium chlorochromate (PCC) oxidation (85 %), Scheme .…”

“…To access S2 and S3 the required distal alkylated 1 and 2 were prepared by reported methods involving K 2 CO 3 induced alkylation of 4-tert-butylcalix [4]arene with propargyl bromide or 4-bromo-1-butyne respectively. [19] The novel 1-pyrenebutanaldoxime, 3, was required to access S2 whilst known 1-pyrenecarbaldoxime [20] was needed to prepare S1, S3 and S4. The aldehyde precursor to the latter was commercially available whilst 1-pyrenebutanal was prepared from the acid following lithal reduction to the known alcohol [21] (95 %) and pyridinium chlorochromate (PCC) oxidation [22] (85 %), Scheme 2.…”