Synthesis of 1,5-Benzodiazepino and S-Triazino Incorporated Derivatives of Pyrazolo (Isoxazolo) Annulated Azacarbazoles of Medicinal Interest.

Abstract

In consideration of the unprecedented biological potentials of the privileged nucleus of 1,5-benzodiazepines, s-triazines, pyrazoles, isoxazoles, azacarbazoles, an efficient protocol to the synthesis of (2,3-b)-pyrazolo (isoxazolo) fused azacarbazoles, incorporated on its 5-position with 1,5-benzodiazepine nucleus and on its 7-position with 4,6-biscyclopropylamino-2-triazinyl amine of medicinal interest has been described.